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Papers Published at Microbiotix

Butler, M.M., LaMarr, W.A., Foster, K.A., Barnes, M.H., Skow, D.J., Lyden, P.T., Kustigian, L.M., Zhi, C., Brown, N.C., Wright, G.E., and Bowlin, T.L.

Antibacterial Activity and Mechanism of Action of a Novel Anilinouracil-Fluoroquinolone Hybrid Compound
Antimicrob. Agents Chemother. 2007 Jan;51(1):119–127

Premasiri, W.R., Moir, D.T., Klempner, M.S., and Ziegler, L.D. 2007.

Surface enhanced Raman scattering of microorganisms;
in “New Approaches in Biomedical Spectroscopy” (K. Kneipp, R. Aroca, H. Kneipp, & E. Wentrup-Byrne, eds.); Oxford University Press: New York pp. 164-179.

Moir, D. T., Di, M., Opperman, T., Schweizer, H.P. and Bowlin, T.L. 2007.

A high-throughput, homogeneous, bioluminescent assay for Pseudomonas aeruginosa gyrase inhibitors and other DNA-damaging agents.
J Biomol Screen 2007 Sep;12(6):855-64.

Chengxin Zhi, Zheng-yu Long, Andrzej Manikowski, Jeanne Comstock, Wei-Chu Xu, Neal C. Brown, Paul M. Tarantino, Jr., Karsten A. Holm, Edward J. Dix, George E. Wright, Marjorie H. Barnes, Michelle M. Butler, Kimberly A. Foster, William A. LaMarr, Benoit Bachand, Richard Bethell, Caroline Cadilhac, Sylvie Charron, Serge Lamothe, Irina Motorina, and Richard Storer.

Hybrid Antibacterials, DNA Polymerase – Topoisomerase Inhibitors
J Med Chem. 2006, 49. 1455-1465

Chengxin Zhi, Zheng-yu Long, Andrzej Manikowski, Neal C. Brown, Paul M. Tarantino, Jr., Karsten Holm, Edward J. Dix, George E. Wright, Kim A. Foster, Michelle M. Butler, William A. LaMarr, Donna J. Skow, Irina Motorina, Serge Lamothe, and Richard Storer.

Synthesis and Antibacterial Activity of 3-Substituted –6-(3-ethyl-4-methylanilino)uracils
J Med Chem. 2006 Volume 48, Number 22, Pages 7063-7074

Moir DT.

Identification of inhibitors of bacterial enoyl-acyl carrier protein reductase.
Curr Drug Targets Infect Disord. 2005 Sep;5(3):297-305

Barnes MH, Lamarr WA, Foster KA.

DNA gyrase and DNA topoisomerase of Bacillus subtilis: expression and characterization of recombinant enzymes encoded by the gyrA, gyrB and parC, parE genes.
Protein Expr Purif.2003 June:29(2):259-64

Foster KA, Barnes MH, Stephenson RO, Butler MM, Skow DJ, LaMarr WA, Brown NC.

DNA polymerase III of Enterococcus faecalis: expression and characterization of recombinant enzymes encoded by the polC and dnaE genes.
Protein Expr Purif. 2003 Jan;27(1):90-7

Butler MM, Skow DJ, Stephenson RO, Lyden PT, LaMarr WA, Foster KA.

Low frequencies of resistance amount Staphylococcus and Enterococcus species to the bactericidal DNA polymerase inhibitor N(3)-hydroxybutyl 6-(3’-ethyl-4’-methylanilino) uracil.
Antimicrob Agents Chemother. 2002 Dec;46(12):3770-5.